Dr. Sandhya Mishra

Designation: Principal Scientist
Phone No:
2567760
Phone Ext. No: 6160
E-Mail: smishra[at]csmcri.res.in

Research Activities


R & D onBioremediation, Biofuels, Biomolecules and bio-pigments from microalgae,


Expertise


Microalgal Biotechnology, Marine Microbiology, Cyanobacterial Biology, Algal Biochemistry, Biopolymer (PHA), Enzymes, Phycobiliproteins, Biofuels


Research publications (Top ten /latest)

  1. Dubey, S., Bharmoria, P., Gehlot, P.S., Agrawal, V., Kumar, A*, Mishra, S.* (2017) 1-Ethyl-3-methylimidazolium diethylphosphate based extraction of Bioplastic “Polyhydroxyalkanoates” from bacteria: Green and Sustainable Approach. ACS Sustainable Chemistry & Engineering, 6 (1), 766-773.
  2. 2. Bhattacharya, S., Pramanik, S.K., Gehlot, P.S., Gajaria, T., Patel, H., Mishra, S.*, Kumar, A. (2017). Process for Preparing Value Added Products from Microalgae Using Textile Effluent Through Biorefinery Approach. ACS Sustainable Chemistry & Engineering. 5 (11), pp 10019–10028.
  3. Chokshi, K., Pancha, I., Ghosh, A.*, & Mishra S.* (2017). Nitrogen starvation-induced cellular crosstalk of ROS-scavenging antioxidants and phytohormone enhanced the biofuel potential of green microalga Acutodesmus dimorphus. Biotechnology for Biofuels, 10(1), 60.
  4. Ghosh, T., Bhayani, K., Paliwal, C., Maurya, R., Chokshi, K., Pancha, I., & Mishra, S.* (2016). Cyanobacterial pigments as natural anti-hyperglycemic agents: An in vitro study. Frontiers in Marine Science, 3, 146.
  5. Bhattacharya, S., Maurya, R., Mishra, S. K., Ghosh, T., Patidar, S. K., Paliwal, C., Chokshi, K., Pancha, I., Mishra, S.* (2016). Solar driven mass cultivation and the extraction of lipids from Chlorella variabilis: A case study. Algal Research, 14, 137-142.
  6. Mitra, M., Shah, F., Bharadwaj, S. V., Patidar, S. K., & Mishra, S.* (2016). Cultivation of Nannochloropsis oceanica biomass rich in eicosapentaenoic acid utilizing wastewater as nutrient resource. Bioresource Technology, 218, 1178-1186.
  7. Patidar, S. K., Mitra, M., Goel, S., Mishra, S.* (2016). Effect of carbon supply mode on biomass and lipid in CSMCRI's Chlorella variabilis (ATCC 12198). Biomass and Bioenergy, 86, 1-10.
  8. Maurya R., Chokshi K., Ghosh T., Trivedi K., Pancha I., Kubavat D., Mishra S.*, Ghosh A.* (2015) Lipid extracted microalgal biomass residue as a fertilizer substitute for Zea mays L. Frontiers in Plant Science, 6, 1266.
  9. Paliwal, C., Ghosh, T., Bhayani, K., Maurya, R., Mishra S.* (2015). Antioxidant, Anti-Nephrolithe Activities and in Vitro Digestibility Studies of Three Different Cyanobacterial Pigment Extracts. Marine drugs, 13(8), 5384-5401.
  10. Bera A., Dubey S., Bhayani K., Mondal D., Mishra S.*, Ghosh P.K.* (2015). Microbial synthesis of polyhydroxyalkanoate using seaweed-derived crude levulinic acid as co-nutrient. International journal of biological macromolecules, 72, 487-494.

Books/ Book chapters (Best five/latest five)

  1. Bhayani, K., Paliwal, C., Ghosh, T., Mishra, S.* (2017) Nutra-Cosmeceutical Potential of Pigments from Microalgae. In Rajesh Rastogi (Ed) Sunscreens: Source, Formulations, Efficacy and Recommendations. Nova Science Publishers (In Press)
  2. Chokshi, K., Pancha, I., Ghosh, A., Mishra, S.* (2017) Oxidative stress induced bioprospecting of microalgae. In Manoj Kumar and Peter J Ralph (Eds) Systems Biology of Marine Ecosystems. Springer International Publishing. 251-276 (DOI: 10.1007/978-3-319-62094-7_13)
  3. Patidar S.K., Mishra, S.* (2017) Carbon Sequestration by Microalgae: A green approach for climate change mitigation. In Reference Module in Earth Systems and Environmental Sciences, Encyclopedia of Sustainable Technologies (DOI: 10.1016/B978-0-12-409548-9.10125-3)
  4. Ghosh, T., Paliwal, C., Maurya, R.M., Mishra, S.* (2015). Microalgal rainbow colors for nutra-pharmaceutical applications. Plant biology and Biotechnology, Plant diversity, organization, function & improvement, vol.1, 777-791 Springer Verlag, India.
  5. Shrivastav A, Mishra SK and Mishra S*. (2011). Utilization of cheap carbon sources for microbial production of Polyhydroxyalkanoate. In: Kowsari E. (Ed.) Polymer synthesis, Nova science Publishers Inc. NY. (ISBN: 978-1-61324-672-6).

Patents

  1. Ghosh, Pushpito Kumar, Sandhya Mishra, Mahesh Ramniklal Gandhi, Sumesh Chandra Upadhyay, Sanjiv Kumar Mishra, Imran Pancha, Anupama Vijaykumar Shrivastav et al. "Integrated process for the production of oil bearing Chlorella variabilis for lipid extraction utilizing by-products of Jatropha methyl ester (JME) production." EP 2619303A1, U.S. Patent 8,741,628, issued June 3, 2014.
  2. Sandhya Mishra, Pushpito Kumar Ghosh, Mahesh Ramniklal Gandhi, Sourish Bhattacharya, Subarna Maiti, Sumesh Chandra Upadhyay, Arup Ghosh et al. "Engine worthy fatty acid methyl ester (biodiesel) from naturally occuring marine microalgal mats and marine microalgae cultured in open salt pans together with value addition of co-products." EP2718453A2, EP2718453B1, U.S. Patent Application 14/119,065, filed May 22, 2012.
  3. Pushpito Kumar Ghosh, Sumesh Chandra Upadhyay, Sandhya Mishra, Vadakke Puthoor Mohandas, Divesh Narayan Srivastava, Vinod Kumar Shahi, Rahul Jasvantrai Sanghavi et al. "Process for the preparation of natural salt formulations for seawater substitution, mineral fortification." U.S. Patent 20,150,004,673, issued January 1, 2015.
  4. Pushpito Kumar Ghosh, Sandhya Mishra, Mahesh Ramniklal Gandhi, Sumesh Chandra Upadhyay, Parimal Paul, Pritpal Singh Anand, Kiritkumar Mangaldas Popat et al. "Integrated process for the production of Jatropha methyl ester and by products." EP2475754A1, EP2475754B1, U.S. Patent Application 13/981,742, filed March 29, 2010.
  5. Sandhya Mishra, Pushpito Kumar Ghosh, Mahesh Ramniklal Gandhi, Ajoykumar Murlidhar Bhatt, and Shantibhai Amritlal Chauhan. "Process for the removal of calcium ions from the brine by marine cyanobacteria." U.S. Patent 6,812,011, issued November 2, 2004.
  6. Ghosh, Pushpito Kumar, Sandhya Mishra, Subarna Maiti, Chetan Paliwal, Sanjiv Kumar Mishra, Tonmoy Ghosh, Kaumeel Chokshi, Pankaj Patel, and Jitendra Narsinh Bharadia. "Solar driven solvent extractor and process for extraction of microalgal lipids using the same." U.S. Patent Application 14/389,824, filed April 2, 2013.
  7. Mahato, Prasenjit, Amrita Ghosh, Sanjiv Kumar Mishra, Anupama Shrivastava, Sandhya Mishra, and Amitava Das. "Zn (ii) based colorimetric sensor and process for the preparation thereof." EP 2576522B1, U.S. Patent Application 13/636,260, filed March 21, 2011.

Poster presentation (best five/latest five)

  1. Khushbu Bhayani, Sourish Bhattacharya and Sandhya Mishra(2017) Natural preservatives for natural products: Bacterial e-polylysine for microalgal pigments XXXII Gujarat Science Congress – 2018, Bhavnagar, 2017.
  2. Sourish Bhattacharya & Sandhya Mishra (2012) Fermentative production of e-polylysine from a bacterial isolate isolated from CSMCRI’s garden soil. Poster presented in International Conference in Industrial Biotechnology 2012 conducted by Biotech research Society of India at Punjabi university, Patiala, Punjab.
  3. Sandhya Mishra*, Sanjiv K. Mishra, Satyabrata Das and Pushpito K. Ghosh (2010) Marine Cyanobacterial phycobiliproteins: CSMCRI achievements. Poster presented in Gordon Research Conference: “Crystal Engineering” Waterville Valley Resort in Waterville Valley, New Hampshire, United States, USA during June 6-11, 2010.
  4. Bhumi Shethia, Anupama Shrivastav, Sanjiv K Mishra, Imran Pancha, Deepti Jain and Sandhya Mishra*. National Conference on emerging field of life sciences - Bordi (Mumbai) held at Department of biotechnology, GES’s N.B. Mehta (Walwada) Science College, Bordi, on 16th -17th November 2009 (best poster award).
  5. Anupama Shrivastav, Sanjiv K. Mishra, Sandhya Mishra* and B. Jha. Biopolymer’s from alkaliphillic Spirulina spp. under salinity stress condition. International Symposium on Applied Phycology and Environmental Biotechnology (ISAPEB), BITS, Pilani, 28-30 October, 2007 (best poster award).Professional recognition/Awards/prize/fellowships

Members of scientific societies

  1. American Biographical Institute conferred an honorary appointment to the Research Board of Advisors, since 2003.
  2. Member of American Society of Microbiologists -ASM (2005)
  3. Fellow award by Society of Applied Biotechnology, India, 2012
  4. Associate Fellow, Gujarat Science Academy

Research project handled

  1.  Extraction of C-Phycocyanin from Spirulina platensis, funded by M/S Strides Arcolab, B’lore, (2000-2003)
  2. Hikal industries (fungicide) effluent treatment, funded by Hikal industries, (2000-2001)
  3.  Heavy water board TBP containing effluent treatment, funded by BARC (January 2003 – September 2003)
  4. Biofuel from marine microalgae, funded by CSIR- MoES NMITLI  (2010-2013)
  5. Integrated process development for maximizing production of bio-pigments and residual biomass as an energy feedstock from algae and its life cycle assessment (LCA), funded by DST (2015-2017).
  6. Isolation of halotolerant microbes (bacteria and microalgae) for its utilization in desalination of marine water through microbial fuel cell, funded by DRDE (2014-2015).

Dissertations guided PhD No- 10; International – 1 (TWAS ROCASA Fellowship)

MSc  No- 25, MTech -10